STATIN DRUG GUIDELINES BROADENED TO INCLUDE MILLIONS MORE PATIENTS

Printer-friendly versionPrinter-friendly version Share this

 

By Leon Thompson

Critics cite pharmaceutical funding of organizations pushing new guidelines

November 17, 2013 (San Diego's East County) -- Many more American may soon be prescribed statin drugs to prevent heart disease. That’s due to new guidelines just released by the American Heart Association and the American College of Cardiology for use of cholesterol lowering drugs – specifically statins.

The old guidelines focused on lowering LDL, or “bad” cholesterol, to target levels.  The new guidelines go beyond treating those who already have cardiovascular disease and now propose statins for treating healthy patients who are at risk of developing cardiovascular disease over the next ten years.

By some estimates, this could double of patients on statin drugs to 30% of the U.S. adult population, the Boston Globe reports.

Millions of Americans suffer from high cholesterol.  Cholesterol is essential for all human and animal life however, high levels of cholesterol are strongly associated with atherosclerosis (hardening of the arteries) and coronary heart disease. 

Animal fats and carbohydrates play roles in total blood cholesterol levels.  These functions take place mainly in the liver where a balance between LDL and HDL are maintained. 

But this balance is largely determined by genetics.  In other words high cholesterol for some is in the genes (and show in the levi jeans) but can be changed by food choice, body build and medications. 

The new guidelines recommend moderate- or high-intensity statin therapy for these four groups:

  • Patients who have cardiovascular disease;
  • Patients with an LDL, or “bad” cholesterol level of 190 mg/dL or higher;
  • Patients with Type 2 diabetes who are between 40 and 75 years of age; and
  • Patients with an estimated 10-year risk of cardiovascular disease of 7.5 percent or higher who are between 40 and 75 years of age (the report provides formulas for calculating 10-year risk).

Biochemist and researchers are working to find new and more effective ways for reducing the risk of cardiovascular disease.

But Canadian researcher Dr Jean-Claude Tardif said, “Even the most powerful statins have not cured the disease,” the New York Times reported.  

Furthermore what about the millions for whom statins are not effective or the millions who are allergic or cannot tolerate them? 

The new guidelines may sound like good news for patients, but there are serious doubts over whether statins actually offer meaningful protection from our nation’s number one killer, heart disease, or whether statins hel people live longer or better. 

Statins are effective for people with known heart disease, though there can be serious side effects. But for people who have less than a 20 percent risk of getting heart disease in the next 10 years, statins not only fail to reduce the risk of death, but also fail even to reduce the risk of serious illness.  At the same time, 18 percent or more of this group would experience serious side effects, including muscle pain or weakness, decreased cognitive function, increased risk of diabetes (especially for women), cataracts or sexual dysfunction, the New York Times has reported.

Perhaps more dangerous, statins provide false reassurances that may discourage patients from taking the steps that actually reduce cardiovascular disease.  

Stopping use of statins has also been linked to onset of Parkinson’s Disease.

A New York Times editorial, moreover, observed that both the American Heart Association and the American College of Cardiology receive substantial funding from the pharmaceutical industry – an industry that stands to benefit substantially from having millions more Americans taking statin drugs.

The Times editorial concluded, “The American people deserve to have important medical guidelines developed by doctors and scientists on whom they can confidently rely to make judgments free from influence, conscious or unconscious, by the industries that stand to gain or lose.”

According to the World Health Organization, 80 percent of cardiovascular disease is caused by smoking, lack of exercise, an unhealthy diet, and other lifestyle factors. Statins give the illusion of protection to many people who may be much better served, for example, by simply walking an extra 10 minutes per day.

 


Error message

Local news in the public interest is more important now than ever, during the COVID-19 crisis. Our reporters, as essential workers, are dedicated to keeping you informed, even though we’ve had to cancel fundraising events. Please give the gift of community journalism by donating at https://www.eastcountymedia.org/donate.